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Helmut Friess Selected Research

Chronic Pancreatitis

6/2020The role of total pancreatectomy with islet autotransplantation in the treatment of chronic pancreatitis: A report from the International Consensus Guidelines in chronic pancreatitis.
1/2018Elevated systemic levels of the matrix metalloproteinase inhibitor TIMP-1 correlate with clinical markers of cachexia in patients with chronic pancreatitis and pancreatic cancer.
7/2016Evidence-Based Surgical Treatments for Chronic Pancreatitis.
1/2016Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis.
8/2014Pancreatic enzyme replacement therapy in patients with exocrine pancreatic insufficiency due to chronic pancreatitis: a 1-year disease management study on symptom control and quality of life.
7/2014Pain sensation in pancreatic diseases is not uniform: the different facets of pancreatic pain.
10/2013Variants in CPA1 are strongly associated with early onset chronic pancreatitis.
1/2013The impact of MFG-E8 in chronic pancreatitis: potential for future immunotherapy?
11/2012Neuronal plasticity in chronic pancreatitis is mediated via the neurturin/GFRα2 axis.
4/2012Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype.
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Helmut Friess Research Topics

Disease

219Neoplasms (Cancer)
11/2022 - 12/2000
160Pancreatic Neoplasms (Pancreatic Cancer)
02/2022 - 12/2000
75Adenocarcinoma
02/2022 - 04/2002
53Chronic Pancreatitis
06/2020 - 04/2001
29Neoplasm Metastasis (Metastasis)
01/2021 - 12/2000
29Pain (Aches)
06/2020 - 04/2001
18Inflammation (Inflammations)
01/2022 - 04/2001
16Pancreatitis
04/2022 - 02/2002
16Fibrosis (Cirrhosis)
01/2022 - 04/2002
16Carcinogenesis
01/2021 - 01/2002
14Hepatocellular Carcinoma (Hepatoma)
01/2022 - 07/2003
12Hypoxia (Hypoxemia)
01/2021 - 01/2003
12Carcinoma (Carcinomatosis)
01/2021 - 04/2002
12Stomach Neoplasms (Stomach Cancer)
01/2018 - 07/2002
10Pancreatic Fistula (Pancreatic Fistulas)
12/2020 - 01/2002
10Wounds and Injuries (Trauma)
08/2020 - 09/2004
9Liver Cirrhosis (Hepatic Cirrhosis)
01/2022 - 07/2003
8Colorectal Neoplasms (Colorectal Cancer)
11/2022 - 09/2002
8Cachexia
10/2021 - 08/2005
8Esophageal Neoplasms (Esophageal Cancer)
01/2021 - 04/2002
7Disease Progression
06/2021 - 08/2005
7Infections
06/2021 - 06/2002
7Colonic Neoplasms (Colon Cancer)
10/2018 - 01/2008
7Rectal Neoplasms (Rectal Cancer)
11/2014 - 03/2007
6Gastrointestinal Neoplasms (Gastrointestinal Cancer)
01/2022 - 05/2003
6Liver Diseases (Liver Disease)
01/2019 - 06/2008
5Diabetes Mellitus
06/2020 - 10/2006
5Necrosis
01/2020 - 01/2002
5Ischemia
03/2017 - 09/2006
4Abscess
11/2021 - 01/2007
4Crohn Disease (Crohn's Disease)
11/2021 - 04/2007
4Nausea
01/2021 - 03/2006
4Cholangiocarcinoma
01/2020 - 01/2019
4Hemorrhage
03/2017 - 01/2006
4Surgical Wound Infection
01/2017 - 05/2012
4Neuritis (Polyneuritis)
01/2013 - 01/2009

Drug/Important Bio-Agent (IBA)

88Messenger RNA (mRNA)IBA
01/2020 - 12/2000
58Proteins (Proteins, Gene)FDA Link
11/2022 - 08/2002
17EnzymesIBA
06/2014 - 04/2002
16Biological ProductsIBA
02/2022 - 12/2000
14Biomarkers (Surrogate Marker)IBA
10/2021 - 12/2006
14GemcitabineFDA Link
01/2021 - 01/2002
12Pharmaceutical PreparationsIBA
11/2022 - 01/2002
12Small Interfering RNA (siRNA)IBA
01/2020 - 04/2003
12LigandsIBA
01/2018 - 01/2002
12RNA (Ribonucleic Acid)IBA
01/2018 - 04/2002
10Fluorouracil (Carac)FDA LinkGeneric
01/2021 - 01/2002
10CytokinesIBA
12/2020 - 01/2003
10Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2017 - 09/2002
10Transforming Growth Factor beta (TGF-beta)IBA
04/2010 - 01/2002
9Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2015 - 12/2002
7CeruletideIBA
01/2019 - 03/2004
7Cisplatin (Platino)FDA LinkGeneric
08/2018 - 05/2004
7DNA (Deoxyribonucleic Acid)IBA
01/2018 - 01/2003
7Nerve Growth Factor (NGF)IBA
01/2016 - 11/2002
7RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
01/2009 - 04/2002
6AlbuminsIBA
01/2021 - 03/2004
6Phosphotransferases (Kinase)IBA
12/2020 - 11/2003
6Glucose (Dextrose)FDA LinkGeneric
01/2020 - 03/2003
6Nerve Growth Factors (Neurotrophins)IBA
01/2014 - 11/2003
6Substance PIBA
04/2013 - 04/2001
5C-Reactive ProteinIBA
01/2021 - 01/2008
5folfirinoxIBA
01/2021 - 12/2015
5ChemokinesIBA
01/2017 - 09/2006
5matrigelIBA
01/2014 - 07/2004
5NeuropeptidesIBA
04/2013 - 04/2007
5Protein Isoforms (Isoforms)IBA
10/2010 - 10/2002
5Transforming Growth Factor beta1 (TGF beta 1)IBA
02/2005 - 04/2002
4Peptides (Polypeptides)IBA
01/2022 - 01/2004
4Therapeutic UsesIBA
11/2021 - 07/2006
4Leucovorin (Folinic Acid)FDA Link
01/2021 - 09/2010
4AntigensIBA
07/2020 - 05/2003
4Matrix Metalloproteinases (MMPs)IBA
01/2018 - 02/2007
4PeriostinIBA
11/2016 - 04/2007
4Neurotransmitter Agents (Neurotransmitter)IBA
04/2013 - 04/2001
4Chemokine CX3CL1IBA
01/2013 - 03/2009
4Oxygen (Dioxygen)IBA
02/2012 - 01/2003
4AntibodiesIBA
11/2011 - 08/2005
4ErbB Receptors (EGF Receptor)IBA
01/2009 - 07/2004
4Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
11/2007 - 08/2002
4Tyrosine Kinase InhibitorsIBA
10/2007 - 11/2002

Therapy/Procedure

81Therapeutics
11/2022 - 09/2002
36Drug Therapy (Chemotherapy)
07/2021 - 01/2002
31Neoadjuvant Therapy
01/2022 - 11/2009
22Pancreatectomy
12/2020 - 12/2003
19Liver Transplantation
02/2021 - 07/2004
16Pancreaticoduodenectomy
11/2021 - 01/2004
8Chemoradiotherapy
10/2011 - 03/2004
7Hepatectomy
01/2022 - 07/2012
7Length of Stay
06/2021 - 11/2005
6Conservative Treatment
11/2021 - 07/2016
6Combined Modality Therapy
01/2021 - 03/2009
6Adjuvant Chemotherapy
05/2018 - 03/2004
6Lasers (Laser)
01/2007 - 06/2002
5Radiotherapy
01/2021 - 09/2003
5Laparotomy
01/2017 - 03/2011
5Stents
05/2016 - 03/2005
4Immunotherapy
01/2022 - 08/2005
4Operative Surgical Procedures
09/2013 - 01/2004
4Pancreaticojejunostomy
01/2010 - 01/2002